When given to a patient experiencing a manic episode, lithium may produce a normalization of symptomatology within 1 to 3 weeks. Typical symptoms of mania include pressure of speech, motor hyperactivity, reduced need for sleep, flight of ideas, grandiosity, elation, poor judgment, aggressiveness, and possibly hostility. Maintenance therapy reduces the frequency of manic episodes and diminishes the intensity of those episodes which may occur. ![]() Lithium carbonate extended-release tablets are also indicated as a maintenance treatment for individuals with a diagnosis of Bipolar Disorder. Bipolar Disorder, Manic (DSM-IV) is equivalent to Manic Depressive illness, Manic, in the older DSM-II terminology. Lithium carbonate extended-release tablets are indicated in the treatment of manic episodes of Bipolar Disorder. Preclinical studies have shown that lithium alters sodium transport in nerve and muscle cells and effects a shift toward intraneuronal metabolism of catecholamines, but the specific biochemical mechanism of lithium action in mania is unknown. Related/similar drugs Vraylar, fluoxetine, quetiapine, lamotrigine, Abilify, Seroquel, Prozac ACTIONS 6 Aluminum Lake, hypromellose, polydextrose, polyethylene glycol, povidone, sodium chloride, sodium lauryl sulfate, sodium starch glycolate, sorbitol, titanium dioxide and triacetin. Inactive ingredients consist of calcium stearate, FD&C Blue No. ![]() ![]() ![]() This slowly dissolving film-coated tablet is designed to give lower serum lithium peak concentrations than obtained with conventional oral lithium dosage forms. Lithium is an element of the alkali-metal group with atomic number 3, atomic weight 6.94, and an emission line at 671 nm on the flame photometer.Įach beige-colored, film-coated, extended-release tablet contains 300 mg of lithium carbonate. Lithium carbonate extended-release tablets contain lithium carbonate, a white odorless alkaline powder with molecular formula Li 2CO 3 and molecular weight 73.89. Facilities for prompt and accurate serum lithium determinations should be available before initiating therapy (see DOSAGE AND ADMINISTRATION). Lithium toxicity is closely related to serum lithium levels, and can occur at doses close to therapeutic levels.
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